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SPDEF Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26810N-1 50ul / $395
APR26810N-2 100ul / $495
APR26810N-3 200ul / $595

SPDEF Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26810N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Transcription Factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPDEF Polyclonal Antibody.

Molecular Weight

Calculated MW: 35kDa/37kDa Observed MW: 50kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SPDEF (NP_036523.1).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

SPDEF; PDEF; bA375E1.3; SAM pointed domain-containing Ets transcription factor

Images

Western blot analysis of extracts of HT-29 cells, using SPDEF antibody.

Specification

Quantity

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