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PNKP Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26758N-1 50ul / $395
APR26758N-2 100ul / $495
APR26758N-3 200ul / $595

PNKP Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26758N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>DNA Damage & Repair

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PNKP Polyclonal Antibody.

Molecular Weight

Calculated MW: 53kDa/57kDa Observed MW: 57kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PNKP (NP_009185.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Product Description

This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Synonyms

PNKP; AOA4; EIEE10; MCSZ; PNK; polynucleotide kinase 3'-phosphatase

Images

Western blot analysis of extracts of various cell lines, using PNKP antibody.

Immunohistochemistry of paraffin-embedded rat kidney using PNKP antibody.

Immunohistochemistry of paraffin-embedded human lung cancer using PNKP antibody.

Specification

Quantity

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