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MATK Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26721N-1 50ul / $395
APR26721N-2 100ul / $495
APR26721N-3 200ul / $595

MATK Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26721N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MATK Polyclonal Antibody.

Molecular Weight

Calculated MW: 51kDa/56kDa Observed MW: 56kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MATK (NP_647611.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Synonyms

MATK; CHK; CTK; HHYLTK; HYL; HYLTK; Lsk; megakaryocyte-associated tyrosine kinase

Images

Western blot analysis of extracts of THP-1 cells, using MATK antibody.

Immunohistochemistry of paraffin-embedded rat kidney using MATK antibody.

Immunohistochemistry of paraffin-embedded mouse kidney using MATK antibody.

Specification

Quantity

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