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GM2A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26677N-1 50ul / $395
APR26677N-2 100ul / $495
APR26677N-3 200ul / $595

GM2A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26677N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Lipid Metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GM2A Polyclonal Antibody.

Molecular Weight

Calculated MW: 20kDa Observed MW: 26kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human GM2A (NP_000396.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.

Synonyms

GM2A; GM2-AP; SAP-3; ganglioside GM2 activator

Images

Western blot analysis of extracts of various cell lines, using GM2A antibody.

Specification

Quantity

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