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GLRX2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26675N-1 50ul / $395
APR26675N-2 100ul / $495
APR26675N-3 200ul / $595

GLRX2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26675N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GLRX2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 18kDa Observed MW: 18kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human GLRX2 (NP_001230328.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression.

Synonyms

GLRX2; CGI-133; GRX2; glutaredoxin 2

Images

Western blot analysis of extracts of MCF-7 cells, using GLRX2 Antibody.

Specification

Quantity

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