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CREB3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26643N-1 50ul / $395
APR26643N-2 100ul / $495
APR26643N-3 200ul / $595

CREB3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26643N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Neurodegenerative Diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CREB3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 39kDa/41kDa/43kDa Observed MW: 41kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CREB3 (NP_006359.3).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:10 - 1:100

Product Description

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.

Synonyms

CREB3; LUMAN; LZIP; sLZIP; cAMP responsive element binding protein 3

Images

Western blot analysis of extracts of various cell lines, using CREB3 antibody.

Immunofluorescence analysis of HeLa cells using CREB3 antibody.

Specification

Quantity

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