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ALAS1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26599N-1 50ul / $395
APR26599N-2 100ul / $495
APR26599N-3 200ul / $595

ALAS1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26599N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Blood

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ALAS1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 12kDa/70kDa Observed MW: 70kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ALAS1 (NP_954635.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

ALAS1; ALAS; ALAS-H; ALAS3; ALASH; MIG4; 5'-aminolevulinate synthase 1

Images

Western blot analysis of extracts of various cell lines, using ALAS1 antibody.

Specification

Quantity

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