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GLI2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26590N-1 50ul / $395
APR26590N-2 100ul / $495
APR26590N-3 200ul / $595

GLI2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26590N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GLI2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 168kDa Observed MW: 90kDa

Species Reactivity

Rabbit

Immunogen

Recombinant protein of mouse GLI2

Cross Reactivity

Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Synonyms

GLI2; CJS; HPE9; PHS2; THP1; THP2; zinc finger protein GLI2

Images

Western blot analysis of extracts of various cell lines, using GLI2 antibody.

Specification

Quantity

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