> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > DDIT3 / CHOP Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR26588N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cell Biology & Developmental Biology>Autophagy |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DDIT3 / CHOP Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
19kDa/21kDa
Observed MW:
27kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant protein of human DDIT3 / CHOP
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:500 - 1:2000
IF 1:50 - 1:200
IHC 1:50 - 1:200
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Product Description |
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
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Synonyms |
DDIT3; CEBPZ; CHOP; CHOP-10; CHOP10; GADD153; C/EBPzeta; DNA damage inducible transcript 3
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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