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CASP4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26584N-1 50ul / $395
APR26584N-2 100ul / $495
APR26584N-3 200ul / $595

CASP4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26584N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CASP4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 13kDa/18kDa/30kDa/36kDa/43kDa Observed MW: 43-48kDa

Species Reactivity

Rabbit

Immunogen

Recombinant protein of mouse CASP4

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Synonyms

CASP4; ICE(rel)II; ICEREL-II; ICH-2; Mih1; Mih1/TX; TX; caspase-4

Images

Western blot analysis of extracts of various cell lines, using CASP4 antibody.

Specification

Quantity

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