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IL18BP Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26538N-1 50ul / $395
APR26538N-2 100ul / $495
APR26538N-3 200ul / $595

IL18BP Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26538N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>Cell Intrinsic Innate Immunity Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL18BP Polyclonal Antibody.

Molecular Weight

Calculated MW: 12kDa/17kDa/21kDa Observed MW: 38kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human IL18BP (NP_001138529.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Synonyms

IL18BP; IL18BPa; interleukin-18-binding protein

Images

Western blot analysis of extracts of various cell lines, using IL18BP antibody.

Immunohistochemistry of paraffin-embedded mouse heart using IL18BP antibody.

Immunofluorescence analysis of A549 cells using IL18BP antibody.

Specification

Quantity

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