> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > IL18BP Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR26538N |
Product Type |
Polyclonal Antibodies | Field of Research |
Immunology & Inflammation>Cell Intrinsic Innate Immunity Signaling Pathway |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL18BP Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
12kDa/17kDa/21kDa
Observed MW:
38kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human IL18BP (NP_001138529.1).
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Cross Reactivity |
Human,Mouse
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
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Product Description |
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Synonyms |
IL18BP; IL18BPa; interleukin-18-binding protein
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Images |
Western blot analysis of extracts of various cell lines, using IL18BP antibody.
Immunohistochemistry of paraffin-embedded mouse heart using IL18BP antibody.
Immunofluorescence analysis of A549 cells using IL18BP antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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