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Coilin Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26521N-1 50ul / $395
APR26521N-2 100ul / $495
APR26521N-3 200ul / $595

Coilin Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26521N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Cell Type Marker

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Coilin Polyclonal Antibody.

Molecular Weight

Calculated MW: 62kDa Observed MW: 80kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human Coilin (NP_004636.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

Synonyms

COIL; CLN80; p80-coilin; coilin

Images

Western blot analysis of extracts of various cell lines, using Coilin antibody.

Immunofluorescence analysis of HeLa cells using Coilin antibody.

Specification

Quantity

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