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SSRP1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26506N-1 50ul / $395
APR26506N-2 100ul / $495
APR26506N-3 200ul / $595

SSRP1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26506N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SSRP1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 81kDa Observed MW: 98kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SSRP1 (NP_003137.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100

Product Description

The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.

Synonyms

SSRP1; FACT; FACT80; T160; FACT complex subunit SSRP1

Images

Western blot analysis of extracts of various cell lines, using SSRP1 antibody.

Immunohistochemistry of paraffin-embedded mouse liver using SSRP1 antibody.

Immunofluorescence analysis of U2OS cells using SSRP1 antibody.

Specification

Quantity

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