> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SSRP1 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR26506N |
Product Type |
Polyclonal Antibodies | Field of Research |
Epigenetics & Nuclear Signaling>RNA Binding |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SSRP1 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
81kDa
Observed MW:
98kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human SSRP1 (NP_003137.1).
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Cross Reactivity |
Human,Mouse
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:10 - 1:100
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Product Description |
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
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Synonyms |
SSRP1; FACT; FACT80; T160; FACT complex subunit SSRP1
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Images |
Western blot analysis of extracts of various cell lines, using SSRP1 antibody.
Immunohistochemistry of paraffin-embedded mouse liver using SSRP1 antibody.
Immunofluorescence analysis of U2OS cells using SSRP1 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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