> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MMP2 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR26370N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cardiovascular>Angiogenesis |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MMP2 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
65kDa/68kDa/73kDa
Observed MW:
73kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human MMP2 (NP_004521.1).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC
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Dilution |
WB 1:500 - 1:2000IHC 1:50 - 1:200
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Product Description |
This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Synonyms |
MMP2; CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1; matrix metallopeptidase 2
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Images |
Western blot analysis of extracts of U-87MG cells, using MMP2 antibody.
Immunohistochemistry of paraffin-embedded human stomach using MMP2 antibody.
Immunohistochemistry of paraffin-embedded mouse spleen using MMP2 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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