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C8orf4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26365N-1 50ul / $395
APR26365N-2 100ul / $495
APR26365N-3 200ul / $595

C8orf4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26365N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality C8orf4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 12kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human C8orf4 (NP_064515.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

Synonyms

C8orf4; TC-1; TC1; protein C8orf4

Images

Immunohistochemistry of paraffin-embedded rat lung using C8orf4 antibody.

Immunohistochemistry of paraffin-embedded human stomach using C8orf4 antibody.

Immunohistochemistry of paraffin-embedded mouse lung using C8orf4 antibody.

Specification

Quantity

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