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OSM Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26313N-1 50ul / $395
APR26313N-2 100ul / $495
APR26313N-3 200ul / $595

OSM Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26313N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OSM Polyclonal Antibody.

Molecular Weight

Calculated MW: 28kDa Observed MW: 28kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human OSM (NP_065391.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200

Product Description

This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Synonyms

OSM; oncostatin-M

Images

Western blot analysis of extracts of various cell lines, using OSM Antibody.

Immunohistochemistry of paraffin-embedded human prostate using OSM antibody.

Immunofluorescence analysis of C6 cells using OSM antibody.

Specification

Quantity

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