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CTCFL Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26305N-1 50ul / $395
APR26305N-2 100ul / $495
APR26305N-3 200ul / $595

CTCFL Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26305N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Transcription Factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CTCFL Polyclonal Antibody.

Molecular Weight

Calculated MW: 35kDa/46-80kDa Observed MW: 68kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CTCFL (NP_001255970.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:20 - 1:100

Product Description

CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

CTCFL; BORIS; CT27; CTCF-T; HMGB1L1; dJ579F20.2; CCCTC-binding factor like

Images

Western blot analysis of extracts of various cell lines, using CTCFL antibody.

Immunofluorescence analysis of MCF-7 cells using CTCFL antibody.

Specification

Quantity

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