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SETDB1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26301N-1 50ul / $395
APR26301N-2 100ul / $495
APR26301N-3 200ul / $595

SETDB1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26301N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Epigenetic writers and erasers of core Histones

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SETDB1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 44kDa/143kDa Observed MW: 210kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SETDB1 (NP_001230420.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

Synonyms

SETDB1; ESET; H3-K9-HMTase4; KG1T; KMT1E; TDRD21; SET domain bifurcated 1

Images

Western blot analysis of extracts of various cell lines, using SETDB1 antibody.

Immunohistochemistry of paraffin-embedded rat brain using SETDB1 antibody.

Specification

Quantity

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