> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] HuR / ELAVL1 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR26267N |
Product Type |
Polyclonal Antibodies | Field of Research |
Endocrine & Metabolism>AMPK Signaling Pathway |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality [KO Validated] HuR / ELAVL1 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
36kDa/38kDa
Observed MW:
36kDa
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Species Reactivity |
Rabbit
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Immunogen |
A synthetic peptide of human HuR / ELAVL1 (NP_001410.2).
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Cross Reactivity |
Human,Mouse
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:500 - 1:1000
IHC 1:50 - 1:200
IF 1:50 - 1:200
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Product Description |
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
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Synonyms |
ELAVL1; ELAV1; HUR; Hua; MelG; ELAV-like protein 1
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Images |
Western blot analysis of extracts of various cell lines, using HuR / ELAVL1 antibody.
Western blot analysis of extracts from normal (control) and HuR / ELAVL1 knockout (KO) 293T cells, using HuR / ELAVL1 antibody.
Immunohistochemistry of paraffin-embedded human esophagus using HuR / ELAVL1 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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