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SNRNP200 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26257N-1 50ul / $395
APR26257N-2 100ul / $495
APR26257N-3 200ul / $595

SNRNP200 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26257N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SNRNP200 Polyclonal Antibody.

Molecular Weight

Calculated MW: 71kDa/244kDa Observed MW: 244kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SNRNP200 (NP_054733.2).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Synonyms

SNRNP200; ASCC3L1; BRR2; HELIC2; RP33; U5-200KD; small nuclear ribonucleoprotein U5 subunit 200

Images

Western blot analysis of extracts of various cell lines, using SNRNP200 antibody.

Specification

Quantity

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