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LIN28 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26247N-1 50ul / $395
APR26247N-2 100ul / $495
APR26247N-3 200ul / $595

LIN28 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26247N

Product Type

Polyclonal Antibodies

Field of Research

Stem Cells>Embryonic Stem Cells

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LIN28 Polyclonal Antibody.

Molecular Weight

Calculated MW: 22kDa Observed MW: 28kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human LIN28 (NP_078950.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:1000 IF 1:50 - 1:100

Product Description

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.

Synonyms

LIN28A; CSDD1; LIN-28; LIN28; ZCCHC1; lin-28A; lin-28 homolog A

Images

Western blot analysis of extracts of mouse pancreas, using LIN28A antibody.

Specification

Quantity

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