> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > LIN28 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR26247N |
Product Type |
Polyclonal Antibodies | Field of Research |
Stem Cells>Embryonic Stem Cells |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LIN28 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
22kDa
Observed MW:
28kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human LIN28 (NP_078950.1).
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Cross Reactivity |
Human,Mouse
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IF
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Dilution |
WB 1:500 - 1:1000
IF 1:50 - 1:100
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Product Description |
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
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Synonyms |
LIN28A; CSDD1; LIN-28; LIN28; ZCCHC1; lin-28A; lin-28 homolog A
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Images |
Western blot analysis of extracts of mouse pancreas, using LIN28A antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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