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APEH Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26191N-1 50ul / $395
APR26191N-2 100ul / $495
APR26191N-3 200ul / $595

APEH Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26191N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality APEH Polyclonal Antibody.

Molecular Weight

Calculated MW: 81kDa Observed MW: 81kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human APEH (NP_001631.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IP

Dilution

WB 1:500 - 1:2000 IP 1:20 - 1:50

Product Description

This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

Synonyms

APEH; AARE; ACPH; APH; D3F15S2; D3S48E; DNF15S2; OPH; acylamino-acid-releasing enzyme

Images

Western blot analysis of extracts of various cell lines, using APEH antibody.

Specification

Quantity

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