> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SF3B2 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR26175N |
Product Type |
Polyclonal Antibodies | Field of Research |
Epigenetics & Nuclear Signaling>RNA Binding |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SF3B2 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
100kDa
Observed MW:
140kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human SF3B2 (NP_006833.2).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
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Product Description |
This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.
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Synonyms |
SF3B2; Cus1; SAP145; SF3B145; SF3b1; SF3b150; splicing factor 3B subunit 2
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Images |
Western blot analysis of extracts of various cell lines, using SF3B2 antibody.
Immunohistochemistry of paraffin-embedded rat heart using SF3B2 antibody.
Immunohistochemistry of paraffin-embedded human lung cancer using SF3B2 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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