> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SKIL Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR26153N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cancer>Tumor suppressors |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SKIL Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
44kDa/46kDa/71kDa/74kDa/76kDa
Observed MW:
77kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human SKIL (NP_001234937.1).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
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Product Description |
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.
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Synonyms |
SKIL; SNO; SnoA; SnoI; SnoN; ski-like protein
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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