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ITGB3BP Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26148N-1 50ul / $395
APR26148N-2 100ul / $495
APR26148N-3 200ul / $595

ITGB3BP Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26148N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITGB3BP Polyclonal Antibody.

Molecular Weight

Calculated MW: 6kDa/12kDa/19kDa/20kDa/24kDa Observed MW: 20kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ITGB3BP (NP_055103.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

Synonyms

ITGB3BP; CENP-R; CENPR; HSU37139; NRIF3; TAP20; centromere protein R

Images

Western blot analysis of extracts of various cell lines, using ITGB3BP antibody.

Specification

Quantity

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