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PNP Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26097N-1 50ul / $395
APR26097N-2 100ul / $495
APR26097N-3 200ul / $595

PNP Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26097N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Neurodegenerative Diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PNP Polyclonal Antibody.

Molecular Weight

Calculated MW: 32kDa Observed MW: 30kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PNP (NP_000261.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IP

Dilution

WB 1:500 - 1:2000 IP 1:50 - 1:100

Product Description

This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

Synonyms

PNP; NP; PRO1837; PUNP; purine nucleoside phosphorylase

Images

Western blot analysis of extracts of various cell lines, using PNP antibody.

Specification

Quantity

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