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FDPS Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26065N-1 50ul / $395
APR26065N-2 100ul / $495
APR26065N-3 200ul / $595

FDPS Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26065N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Lipids

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FDPS Polyclonal Antibody.

Molecular Weight

Calculated MW: 40kDa/48kDa Observed MW: 38kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human FDPS (NP_001129293.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Product Description

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

FDPS; FPPS; FPS; POROK9; farnesyl diphosphate synthase

Images

Western blot analysis of extracts of various cell lines, using FDPS antibody.

Immunohistochemistry of paraffin-embedded rat brain using FDPS Antibody.

Immunohistochemistry of paraffin-embedded rat kidney using FDPS Antibody.

Specification

Quantity

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