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DYNLL1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26063N-1 50ul / $395
APR26063N-2 100ul / $495
APR26063N-3 200ul / $595

DYNLL1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26063N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DYNLL1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 10kDa Observed MW: 13kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DYNLL1 (NP_003737.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.

Synonyms

DYNLL1; DLC1; DLC8; DNCL1; DNCLC1; LC8; LC8a; PIN; hdlc1; dynein light chain LC8-type 1

Images

Western blot analysis of extracts of various cell lines, using DYNLL1 antibody.

Specification

Quantity

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