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CLCN1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26060N-1 50ul / $395
APR26060N-2 100ul / $495
APR26060N-3 200ul / $595

CLCN1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26060N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLCN1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 108kDa Observed MW: 109kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CLCN1 (NP_000074.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.

Synonyms

CLCN1; CLC1; chloride channel protein 1

Images

Western blot analysis of extracts of various cell lines, using CLCN1 antibody.

Specification

Quantity

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