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CASP2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26046N-1 50ul / $395
APR26046N-2 100ul / $495
APR26046N-3 200ul / $595

CASP2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26046N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CASP2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 10kDa/34kDa/50kDa Observed MW: 60kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CASP2 (NP_116764.2).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

CASP2; CASP-2; ICH1; NEDD-2; NEDD2; PPP1R57; caspase-2

Images

Western blot analysis of extracts of Jurkat cells, using CASP2 antibody.

Immunohistochemistry of paraffin-embedded human gastric cancer using CASP2 Antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using CASP2 Antibody.

Specification

Quantity

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