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FH Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26016N-1 50ul / $395
APR26016N-2 100ul / $495
APR26016N-3 200ul / $595

FH Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26016N

Product Type

Polyclonal Antibodies

Field of Research

Cancer>Tumor suppressors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FH Polyclonal Antibody.

Molecular Weight

Calculated MW: 50kDa/54kDa Observed MW: 50kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human FH (NP_000134.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:10 - 1:100

Product Description

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Synonyms

FH; FMRD; HLRCC; LRCC; MCL; MCUL1; fumarate hydratase

Images

Western blot analysis of extracts of various cell lines, using FH antibody.

Immunofluorescence analysis of U2OS cells using FH antibody.

Specification

Quantity

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