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FOXP2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26005N-1 50ul / $395
APR26005N-2 100ul / $495
APR26005N-3 200ul / $595

FOXP2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26005N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Transcription Factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FOXP2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 9-18kDa/40- 48kDa/70- 82kDa Observed MW: 80kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human FOXP2 (NP_683696.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Synonyms

FOXP2; CAGH44; SPCH1; TNRC10; forkhead box P2

Images

Western blot analysis of extracts of various cell lines, using FOXP2 antibody.

Specification

Quantity

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