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HTR2B Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25998N-1 50ul / $395
APR25998N-2 100ul / $495
APR25998N-3 200ul / $595

HTR2B Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25998N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Endocrine and metabolic diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HTR2B Polyclonal Antibody.

Molecular Weight

Calculated MW: 54kDa Observed MW: 54kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HTR2B (NP_000858.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100

Product Description

This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.

Synonyms

HTR2B; 5-HT(2B); 5-HT-2B; 5-HT2B; 5-hydroxytryptamine receptor 2B

Images

Western blot analysis of extracts of various cell lines, using HTR2B antibody.

Immunohistochemistry of paraffin-embedded rat brain using HTR2B antibody.

Immunohistochemistry of paraffin-embedded mouse brain using HTR2B antibody.

Specification

Quantity

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