> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > BMPR2 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR25995N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cell Biology & Developmental Biology>Cytoskeleton |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BMPR2 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
59kDa/115kDa
Observed MW:
100kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human BMPR2 (NP_001195.2).
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Cross Reactivity |
Human
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IF
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Dilution |
WB 1:500 - 1:2000
IF 1:50 - 1:200
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Product Description |
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.
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Synonyms |
BMPR2; BMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK; bone morphogenetic protein receptor type-2
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Images |
Western blot analysis of extracts of various cell lines, using BMPR2 antibody.
Immunofluorescence analysis of U-2OS cells using BMPR2 antibody.
Immunofluorescence analysis of HeLa cells using BMPR2 antibody. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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