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ABCG2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25991N-1 50ul / $395
APR25991N-2 100ul / $495
APR25991N-3 200ul / $595

ABCG2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25991N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>CDs

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ABCG2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 67kDa/72kDa Observed MW: 72kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ABCG2 (NP_004818.2).

Cross Reactivity

Human,Mouse,Rat,Monkey

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

ABCG2; ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1; ATP-binding cassette sub-family G member 2

Images

Western blot analysis of extracts of various cell lines, using ABCG2 antibody.

Specification

Quantity

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