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LAT Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25980N-1 50ul / $395
APR25980N-2 100ul / $495
APR25980N-3 200ul / $595

LAT Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25980N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>G protein signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LAT Polyclonal Antibody.

Molecular Weight

Calculated MW: 24kDa/27kDa/28kDa Observed MW: 35-38kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human LAT (NP_001014987.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

LAT; LAT1; pp36; IMD52; linker for activation of T-cells

Images

Western blot analysis of extracts of Jurkat cells, using LAT antibody.

Specification

Quantity

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