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FGG Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25973N-1 50ul / $395
APR25973N-2 100ul / $495
APR25973N-3 200ul / $595

FGG Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25973N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Blood

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FGG Polyclonal Antibody.

Molecular Weight

Calculated MW: 49kDa/51kDa Observed MW: 53kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human FGG (NP_000500.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.

Synonyms

FGG; fibrinogen gamma chain

Images

Immunofluorescence analysis of U-2 OS cells using FGG antibody.

Immunofluorescence analysis of NIH/3T3 cells using FGG antibody.

Specification

Quantity

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