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ERCC2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25971N-1 50ul / $395
APR25971N-2 100ul / $495
APR25971N-3 200ul / $595

ERCC2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25971N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ERCC2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 46kDa/86kDa Observed MW: 87kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ERCC2 (NP_001124339.1).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

ERCC2; COFS2; EM9; TFIIH; TTD; TTD1; XPD; ERCC excision repair 2, TFIIH core complex helicase subunit

Images

Western blot analysis of extracts of various cell lines, using ERCC2 antibody.

Immunofluorescence analysis of HeLa cells using ERCC2 antibody.

Specification

Quantity

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