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TPP1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25958N-1 50ul / $395
APR25958N-2 100ul / $495
APR25958N-3 200ul / $595

TPP1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25958N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Neurodegenerative Diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TPP1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 34kDa/61kDa Observed MW: 50kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human TPP1 (NP_000382.3).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Synonyms

TPP1; CLN2; GIG1; LPIC; SCAR7; TPP-1; tripeptidyl-peptidase 1

Images

Western blot analysis of extracts of various cell lines, using TPP1 antibody.

Specification

Quantity

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