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HAX1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25909N-1 50ul / $395
APR25909N-2 100ul / $495
APR25909N-3 200ul / $595

HAX1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25909N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HAX1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 14kDa/21kDa/26kDa/28kDa/31kDa/32kDa Observed MW: 36kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HAX1 (NP_006109.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100

Product Description

The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

HAX1; HCLSBP1; HS1BP1; SCN3; HCLS1-associated protein X-1

Images

Western blot analysis of extracts of various cell lines, using HAX1 antibody.

Immunohistochemistry of paraffin-embedded mouse heart using HAX1 antibody.

Immunofluorescence analysis of A549 cells using HAX1 antibody.

Specification

Quantity

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