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UBE2C Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25883N-1 50ul / $395
APR25883N-2 100ul / $495
APR25883N-3 200ul / $595

UBE2C Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25883N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UBE2C Polyclonal Antibody.

Molecular Weight

Calculated MW: 15kDa/16kDa/17kDa/19kDa Observed MW: 20kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human UBE2C (NP_008950.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF,IP

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Product Description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.

Synonyms

UBE2C; UBCH10; dJ447F3.2; ubiquitin-conjugating enzyme E2 C

Images

Western blot analysis of extracts of various cell lines, using UBE2C antibody.

Immunohistochemistry of paraffin-embedded human colon carcinoma using UBE2C antibody.

Immunohistochemistry of paraffin-embedded human gastric cancer using UBE2C antibody.

Specification

Quantity

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