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DHCR24 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25800N-1 50ul / $395
APR25800N-2 100ul / $495
APR25800N-3 200ul / $595

DHCR24 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25800N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DHCR24 Polyclonal Antibody.

Molecular Weight

Calculated MW: 54kDa/60kDa Observed MW: 55kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DHCR24 (NP_055577.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Synonyms

DHCR24; DCE; Nbla03646; SELADIN1; seladin-1; delta(24)-sterol reductase

Images

Western blot analysis of extracts of various cell lines, using DHCR24 antibody.

Specification

Quantity

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