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SCP2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25784N-1 50ul / $395
APR25784N-2 100ul / $495
APR25784N-3 200ul / $595

SCP2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25784N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Lipid Metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCP2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 6kDa/15kDa/34kDa/50kDa/54kDa/56kDa/58kDa Observed MW: 59kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SCP2 (NP_001007099.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Synonyms

SCP2; NLTP; NSL-TP; SCP-2; SCP-CHI; SCP-X; SCPX; sterol carrier protein 2

Images

Western blot analysis of extracts of mouse liver, using SCP2 Antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using SCP2 antibody.

Specification

Quantity

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