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PA2G4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25778N-1 50ul / $395
APR25778N-2 100ul / $495
APR25778N-3 200ul / $595

PA2G4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25778N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Nuclear Receptor Signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PA2G4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 38kDa/43kDa Observed MW: 44kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PA2G4 (NP_006182.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.

Synonyms

PA2G4; EBP1; HG4-1; p38-2G4; proliferation-associated 2G4

Images

Western blot analysis of extracts of various cell lines, using PA2G4 antibody.

Immunohistochemistry of paraffin-embedded rat lung using PA2G4 Antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using PA2G4 Antibody.

Specification

Quantity

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