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SMARCE1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25763N-1 50ul / $395
APR25763N-2 100ul / $495
APR25763N-3 200ul / $595

SMARCE1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25763N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Chromatin Remodeling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SMARCE1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 34kDa/37kDa/39kDa/41kDa/42kDa/46kDa Observed MW: 55kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SMARCE1 (NP_003070.3).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

Synonyms

SMARCE1; BAF57; CSS5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

Images

Western blot analysis of extracts of various cell lines, using SMARCE1 antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using SMARCE1 Antibody.

Immunohistochemistry of paraffin-embedded mouse brain using SMARCE1 Antibody.

Specification

Quantity

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