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DAZ1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25716N-1 50ul / $395
APR25716N-2 100ul / $495
APR25716N-3 200ul / $595

DAZ1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25716N

Product Type

Polyclonal Antibodies

Field of Research

Stem Cells>Germline Stem Cells

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DAZ1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 67kDa/82kDa Observed MW: 83kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DAZ1 (NP_004072.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described; thus the RefSeq for this gene contains only two RRM domains.

Synonyms

DAZ1; DAZ; SPGY; deleted in azoospermia 1

Images

Western blot analysis of extracts of various cell lines, using DAZ1 antibody.

Specification

Quantity

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