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ITGA6 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25180N-1 50ul / $395
APR25180N-2 100ul / $495
APR25180N-3 200ul / $595

ITGA6 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25180N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>CDs

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITGA6 Polyclonal Antibody.

Molecular Weight

Calculated MW: 106kDa/119kDa/121kDa/122kDa/124kDa/126kDa Observed MW: 105kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ITGA6 (NP_001073286.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.

Synonyms

ITGA6; CD49f; ITGA6B; VLA-6; integrin alpha-6

Images

Western blot analysis of extracts of various cell lines, using ITGA6 antibody.

Immunofluorescence analysis of U2OS cells using ITGA6 antibody.

Specification

Quantity

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