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TTR Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25163N-1 50ul / $395
APR25163N-2 100ul / $495
APR25163N-3 200ul / $595

TTR Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25163N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Blood

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TTR Polyclonal Antibody.

Molecular Weight

Calculated MW: 15kDa Observed MW: _

Species Reactivity

Rabbit

Immunogen

Recombinant protein of human TTR

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

IHC,IF

Dilution

IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

Synonyms

TTR; CTS; CTS1; HEL111; HsT2651; PALB; TBPA; transthyretin

Images

Immunohistochemistry of paraffin-embedded rat brain using TTR Antibody.

Immunofluorescence analysis of human liver cancer using TTR Polyclonal Antibody.

Specification

Quantity

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