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NPY Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25156N-1 50ul / $395
APR25156N-2 100ul / $495
APR25156N-3 200ul / $595

NPY Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25156N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NPY Polyclonal Antibody.

Molecular Weight

Calculated MW: 10kDa Observed MW: _

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NPY (NP_000896.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

IHC,IF

Dilution

IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi.

Synonyms

NPY; PYY4; neuropeptide Y

Images

Immunohistochemistry of paraffin-embedded rat brain using NPY antibody.

Immunohistochemistry of paraffin-embedded mouse brain using NPY antibody.

Specification

Quantity

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