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DNMT3A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25149N-1 50ul / $395
APR25149N-2 100ul / $495
APR25149N-3 200ul / $595

DNMT3A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25149N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Epigenetic writers and erasers of core Histones

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DNMT3A Polyclonal Antibody.

Molecular Weight

Calculated MW: 16kDa/81kDa/101kDa Observed MW: 95kDa

Species Reactivity

Rabbit

Immunogen

Recombinant protein of human DNMT3A

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

Synonyms

DNMT3A; DNMT3A2; M.HsaIIIA; TBRS; DNA methyltransferase 3 alpha

Images

Western blot analysis of extracts of various cell lines, using DNMT3A antibody.

Immunohistochemistry of paraffin-embedded rat brain using DNMT3A Antibody.

Immunohistochemistry of paraffin-embedded human kidney using DNMT3A Antibody.

Specification

Quantity

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